Home | Disease Models Mechanisms

Time 2020-10-09 03:02:50

Web Name: Home | Disease Models Mechanisms

WebSite: http://dmm.biologists.org

ID:75424

Keywords:

Disease,Home,Mechanisms,

Description:

Due to COVID-19, DMM staff are working remotely, but our editorial operations continue to run as usual. Please contact us by email atdmm@biologists.comif you have any queries. Thank you for your patience and understanding.For more information on measures DMM is taking to support the community at this time, please see here. Disease Models Mechanisms (DMM)is an Open Access biomedical research journal focusing on the use of model systems to better understand, diagnose and treat human disease.The primary aim of DMM is to promote human health by inspiring collaboration between basic and clinical researchers in translational science. The journal is committed to presenting rigorously peer-reviewed research that has significant translational impact. The interdisciplinary nature of DMM means that a diverse range of diseases, approaches and models fall within its broad scope. DMM is guided by an international team of expert research-active Editors, led by Monica Justice and Ross Cagan, and supported byan outstanding Editorial Advisory Board.Read more Akkermansia muciniphila promotes type H vessels formation and bone fracture healing by reducing gut permeability and inflammation Jiang-Hua Liu, Tao Yue, Zhong-Wei Luo, Jia Cao, Zi-Qi Yan, Ling Jin, Teng-Fei Wan, Ci-Jun Shuai, Zheng-Guang Wang, Yong Zhou, Ran Xu, Hui Xie Identification of MYOM2 as a candidate gene in hypertrophic cardiomyopathy and tetralogy of fallot and its functional evaluation in the Drosophila heart Emilie Auxerre-Plantié, Tanja Nielsen, Marcel Grunert, Olga Olejniczak, Andreas Perrot, Cemil Özcelik, Dennis Harries, Faramarz Matinmehr, Cristobal Dos Remedios, Christian Mühlfeld, Theresia Kraft, Rolf Bodmer, Georg Vogler, Silke R. Sperling Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma Lena M. Westermann, Lutz Fleischhauer, Jonas Vogel, Zsuzsa Jenei-Lanzl, Nataniel Floriano Ludwig, Lynn Schau, Fabio Morellini, Anke Baranowsky, Timur A. Yorgan, Giorgia Di Lorenzo, Michaela Schweizer, Bruna de Souza Pinheiro, Nicole Ruas Guarany, Fernanda Sperb-Ludwig, Fernanda Visioli, Thiago Oliveira Silva, Jamie Soul, Gretl Hendrickx, J. Simon Wiegert, Ida V. D. Schwartz, Hauke Clausen-Schaumann, Frank Zaucke, Thorsten Schinke, Sandra Pohl, Tatyana Danyukova In October s Editor s choice, Yamanouchi et al. describe a newly established rat model carrying in-frame mutations in the Dmd gene. The modelexhibits the dystrophic phenotype and abnormal dystrophin expression profile, similar to patients with Becker muscular dystrophy.Comparative analyses of temporal cohorts of the Ts65Dn mouse model of Down syndrome by Haydar and co-workers reveal phenotypic variability affecting neurodevelopment and learning and memory behaviors, calling into question the validity of this model. A Special Article from Martinez and colleagues discusses current model systems to study the novel coronavirus SARS-CoV-2, the pathogen that causes COVID-19.Vaccine development for tuberculosis requires an understanding of neonatal and infant immunity. Gonzalez-Juarrero and colleagues review animal models of neonatal and infant immunity, and highlight the potential of piglets as important models for vaccine development.Fibrodysplasia ossificans progressiva is a rare disease characterised by progressive heterotopic bone formation. Phil Ingham and colleagues present a comprehensive summary of the recent literature on this debilitating condition and discuss approaches to solving this clinical puzzle. Circulating exosomal microRNAs as potential biomarkers of hepatic injury and inflammation in a... Roberta Resaz, Davide Cangelosi, Martina Morini, Daniela Segalerba, Luca Mastracci, Federica Grillo, Maria Carla Bosco, Cristina Bottino, Irma Colombo, Alessandra Eva Rabphilin involvement in filtration and molecular uptake... Estela Selma-Soriano, Beatriz Llamusi, Juan Manuel Fernández-Costa, Lauren Louise Ozimski, Rubén Artero, Josep Redón A novel mouse model of Duchenne muscular dystrophy... Tatianna Wai Ying Wong, Abdalla Ahmed, Grace Yang, Eleonora Maino, Sydney Steiman, Elzbieta Hyatt, Parry Chan, Kyle Lindsay, Nicole Wong, Diane Golebiowski, Joel Schneider, Paul Delgado-Olguín, Evgueni A. Ivakine, Ronald D. Cohn Cercosporamide inhibits bone morphogenetic protein receptor type I kinase activity in zebrafish Jelmer Hoeksma, Gerard C. M. van der Zon, Peter ten Dijke, Jeroen den Hertog Longitudinal neuroanatomical and behavioral analyses show phenotypic drift and variability in the... Patricia R. Shaw, Jenny A. Klein, Nadine M. Aziz, Tarik F. Haydar Pathological evaluation of rats carrying in-frame mutations in the dystrophin gene: a new model of... Naomi Teramoto, Hidetoshi Sugihara, Keitaro Yamanouchi, Katsuyuki Nakamura, Koichi Kimura, Tomoko Okano, Takanori Shiga, Taku Shirakawa, Masafumi Matsuo, Tetsuya Nagata, Masao Daimon, Takashi Matsuwaki, Masugi Nishihara Disturbed nitric oxide signalling gives rise to congenital bicuspid aortic valve and aortopathy Joshua C. Peterson, Lambertus J. Wisse, Valerie Wirokromo, Tessa van Herwaarden, Anke M. Smits, Adriana C. Gittenberger-de Groot, Marie-José T. H. Goumans, J. Conny VanMunsteren, Monique R. M. Jongbloed, Marco C. DeRuiter Inhibition of Alk signaling promotes the induction of human salivary-gland-derived organoids Shohei Yoshimoto, Junko Yoshizumi, Hiromasa Anzai, Koichiro Morishita, Kazuhiko Okamura, Akimitsu Hiraki, Shuichi Hashimoto Pre-existing antibody-mediated adverse effects prevent the clinical development of a bacterial anti... Angelino T. Tromp, Yuxi Zhao, Ilse Jongerius, Erik C. J. M. Heezius, Pauline Abrial, Maartje Ruyken, Jos A. G. van Strijp, Carla J. C. de Haas, András N. Spaan, Kok P. M. van Kessel, Thomas Henry, Pieter-Jan A. Haas

TAGS:Disease Home Mechanisms 

<<< Thank you for your visit >>>

Hot Websites