Gut | A leading journal in gastroenterology and hepatology - BMJ

Time 2020-09-15 16:03:42

Web Name: Gut | A leading journal in gastroenterology and hepatology - BMJ

WebSite: http://gut.bmj.com

ID:47656

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journal,in,Gut,

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Gut is a leading international journal in gastroenterology and hepatology and has an established reputation for publishing first class clinical research of the alimentary tract, the liver, biliary tree and pancreas. Gut delivers up-to-date, authoritative, clinically oriented coverage in all areas of gastroenterology and hepatology. Regular features include articles by leading authorities describing novel mechanisms of disease and new management strategies, both diagnostic and therapeutic, likely to impact on clinical practice within the foreseeable future.Gut is an official journal of the British Society of Gastroenterology.Editor-in-Chief: Professor Emad El-Omar, University of New South Wales, Sydney, AustraliaEditorial BoardTOP CITED ARTICLESRead the most-cited articles from the past three years for free.SOCIAL MEDIA AND MULTIMEDIAKeep up-to-date with Gut on Twitter and Facebook, and access videos on our YouTube channel.The Gut blog is now live - read the latest posts from the team.Gut publishes podcasts discussing highlights from its issues. Subscribe in all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify.COVID-19: a message from BMJ Guidance from BSG: COVID-19 and Endoscopy Our new online collection highlights all research relating to the COVID-19 pandemic published by Gut, Frontline Gastroenterology and BMJ Open Gastroenterology. It is updated regularly as new articles are published.All content is free to read and features original research, commentaries, letters and editorials from all three journals published with the British Society of Gastroenterology (BSG)Visit the full BMJ Coronavirus resource collection for all the latest content from across our portfolio Visit the COVID-19 Gastroenterology Collection Bile acid composition regulates lipid sensing and food intake regulation 1 September, 2020 To cite: Higuchi S, Ahmad TR, Argueta DA, et al. Gut 2020;69:1620-1628.Read the full article here: linkObjectives: Lipid mediators in the GI tract regulate satiation and satiety. Bile acids (BAs) regulate the absorption and metabolism of dietary lipid in the intestine, but their effects on lipid-regulated satiation and satiety are completely unknown. Investigating this is challenging because introducing excessive BAs or eliminating BAs strongly impacts GI functions. We used a mouse model (Cyp8b1–/– mice) with normal total BA levels, but alterations in the composition of the BA pool that impact multiple aspects of intestinal lipid metabolism. We tested two hypotheses: BAs affect food intake by (1) regulating production of the bioactive lipid oleoylethanolamide (OEA), which enhances satiety; or (2) regulating the quantity and localisation of hydrolysed fat in small intestine, which controls gastric emptying and satiation.Conclusions: BAs regulate gastric emptying and satiation by determining fat-dependent GPR119 activity in distal intestine. Related Content Read the article here

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Gut journal publishes essential research across all areas of gastroenterology and hepatology and is one of the leading specialist titles in its field.

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