Acumen Pharmaceuticals, Inc.
Time 2020-12-25 06:03:20Web Name: Acumen Pharmaceuticals, Inc.
WebSite: http://www.acumenpharm.com
ID:145272
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Acumen,Pharmaceuticals,Inc,Description:
Ascending to New Heights in the Fight Against Alzheimer’s DiseaseAcumen is forging a new path towards safe and effective treatments for Alzheimer’s disease and other neurodegenerative diseases through our focus on the biology of toxic amyloid-beta oligomers - now widely recognized as primary triggers of Alzheimer’s disease. Image depicts a mature hippocampal neuron (red) and toxic amyloid-beta oligomers (green) bound to dendritic spines (overlap appears in yellow). Lacor et al., 2004.Our lead drug candidate ACU193 is a Phase 1 ready, well-characterized, anti-toxic amyloid-beta oligomer (Aβo) monoclonal antibody with best-in-class potential for superior efficacy and safety in Alzheimer’s disease. ACU193 addresses the underlying cause of Alzheimer’s by preventing toxic Aβo from binding to dendritic spines and helping preserve neuronal function.We expect to initiate first-in-human trials for ACU193 in 2021 as the first monoclonal antibody that selectively targets Aβo in Alzheimer’s patients. 427 PARK STREET, CHARLOTTESVILLE, VA 22902 | 434.297.1000 | INFO@ACUMENPHARM.COMTAGS:Acumen Pharmaceuticals Inc
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