Stem Cells Portal | The Stem Cells and Regenerative Medicine Online Community
Time 2020-09-17 17:03:54Web Name: Stem Cells Portal | The Stem Cells and Regenerative Medicine Online Community
WebSite: http://stemcellsportal.com
ID:50073
Keywords:
Portal,The,Stem,Description:
Regenerative Medicine Manufacturing Society (RMMS) is partnering with STEM CELLS Translational Medicine to build a freely accessible collection of shared resources across three areas: models; cell therapies; and technologies. These resources will bring together the scientific community and highlight how the field of regenerative medicine is uniquely positioned to fight the COVID-19 pandemic. Submit a resource or learn more Stem cell mobilization with plerixafor and healing of diabetic ischemic wounds: A phase IIa, randomized, double‐blind, placebo‐controlled trial Benedetta Maria Bonora, et al., STEM CELLS Translational MedicineThe role of hematopoietic stem cells in diabetic complications is well characterized. In the setting of limb ischemia, cell therapy trials with a variety of cell products yielded variable results. There is an unmet need for therapies for the diabetic foot syndrome beyond the state of the art. This study has hypothesized that the CXCR4 antagonist plerixafor could be repurposed to treat ischemic diabetic wounds. In this phase IIa clinical trial, successful stem cell mobilization with plerixafor did not improve healing of ischemic diabetic wounds. Contrary to what was expected, mobilization of diabetic stem cells might exert adverse effects on tissue repair.A genomic biomarker that identifies human bone marrow‐derived mesenchymal stem cells with high scalability Padmapriya Sathiyanathan, et al., STEM CELLSExpression of GSTT1 is haplotype‐specific. This study found that human bone marrow‐derived mesenchymal stem cells (hMSCs) containing a genomic deletion of GSTT1 show high growth capacity. The GSTT1‐null hMSCs also have enhanced clonogenicity and longer telomeres. Therefore, GSTT1 can be considered a genomic biomarker of hMSC scalability. The Stem Cells Portal is a shared platform for the STEM CELLS and STEM CELLS Translational Medicine sister journals, providing up-to-the-minute coverage of the latest research from bench science and developments to clinical applications.<<< Thank you for your visit >>>
A hub covering the latest stem cell research and news from bench science and clinical applications, and forum for research labs and societies worldwide.Websites to related : Abt Associates | Bold Thinking t
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