Clinical Trial Results Clinical Trial Results

Web Name: Clinical Trial Results Clinical Trial Results

WebSite: http://clinicaltrialresults.org

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Editor in Chief C. Michael Gibson

Heart Success

Dr. Carolyn Lam and Dr. C. Michael Gibson Discuss: Updates to the ESC CHF Guidelines and How to Initiate Medications to Optimize Outcomes View Video

Dr. Carolyn Lam Presents: The Results of the EMPEROR PRESERVED Trial Video Video

Dr. Carolyn Lam and Dr. C. Michael Gibson Discuss How to Initiate Heart Failure Drug View Video

Dr. Carolyn Lam and Dr. C. Michael Gibson Talk About Success in the Battle Against Heart Failure View Video

ESC 2021

Dr. Robert Yeh, Dr. Ajay Kirtane, and Dr. C. Michael Gibson Discuss ESC 2021 Wrap-up STOPDAPT2-ACS MASTERDAPT View Video

Dr. Ajay Kirtane and Dr. C. Michael Gibson Discuss: ESC 2021 Wrap-Up Sunday, August 29 View Video

Dr. Ajay Kirtane and Dr. C. Michael Gibson Discuss: ESC 2021 Wrap-Up Saturday, August 28 View Video

Dr. Ajay Kirtane and Dr. C. Michael Gibson Discuss: ESC 2021 Wrap-Up Friday, August 27 View Video

Dr. Cecilia Bahit Presents: ESC 2021 Wrap-up in Spanish Video

Dr. Hirotoshi Watanabe and Dr. C. Michael Gibson Discuss: STOPDAPT-2 ACS: one-month dual antiplatelet therapy followed by clopidogrel monotherapy in acute coronary syndrome View Video | Download Slides

Dr. DJ Lakkireddy and Dr. C. Michael Gibson Discuss: Amulet IDE: Amplatzer Amulet left atrial appendage occluder randomised controlled trial View Video | Download Slides

Dr. Jun Cai and Dr. Yaz Daaboul Discuss: STEP Study: intensive vs. standard blood pressure control among older hypertensive patients View Video | Download Slides

Dr. Renato Lopes and Dr. C. Michael Gibson Discuss: PRONOUNCE: comparing cardiovascular safety of degarelix vs. leuprolide in patients with advanced prostate cancer and cardiovascular disease View Video | Download Slides

Dr. Ole Frobert and Dr. C. Michael Gibson Discuss: IAMI: Influenza Vaccination after Myocardial Infarction randomised trial View Video | Download Slides

Dr. Bruce Neal and Dr. Wally Omar Discuss: SSaSS: Salt Substitute and Stroke Study into the effect of salt substitutes on cardiovascular events and death View Video | Download Slides

Dr. Jesper Hastrup Svendsen and Dr. C. Michael Gibson Discuss: LOOP Study: screening for AF with an implantable loop recorder to prevent stroke View Video | Download Slides

Allison Halliday presents: ACST-2: Stenting vs. Surgery for Tight Carotid Stenosis Download Slides

Dr. Nicholas Curzen and Dr. C. Michael Gibson Discuss: RIPCORD 2: does routine pressure wire assessment influence management strategy of coronary angiography for diagnosis of chest pain? View Video | Download Slides

Dr. Steffen Desch and Dr. C. Michael Gibson Discuss: TOMAHAWK: immediate angiography after out-of-hospital cardiac arrest View Video | Download Slides

Dr. Renato Lopes and Dr. C. Michael Gibson Discuss: The MICHELLE trial: Medically Ill hospitalized Patients for COVID-19 THrombosis Extended ProphyLaxis with rivaroxaban ThErapy View Video | Download Slides

Dr. Nassir Marrouche Presents: Efficacy of DE-MRI-guided Fibrosis Ablation vs. Conventional Catheter Ablation of Persistent Atrial Fibrillation Download Slides

Dr. Michele Brignole Presents: APAF-CRT: AV junction ablation and CRT in patients with permanent atrial fibrillation and narrow QRS Download Slides

Dr. Bertram Pitt and Dr. C. Michael Gibson Discuss: FIGARO-DKD: finerenone in patients with chronic kidney disease and type 2 diabetes View Video | Download Slides

Dr. Marco Valgimigli and Dr. C. Michael Gibson Discuss: MASTER DAPT: dual antiplatelet therapy after coronary stenting in high bleeding risk patients View Video | Download Slides

Dr. George Dangas and Dr. C. Michael Gibson Discuss: ENVISAGE-TAVI AF: edoxaban vs. vitamin K antagonists after TAVI in patients with atrial fibrillation View Video | Download Slides

Dr. Axel Bauer and Dr. Yaz Daaboul Discuss: Implantable cardiac monitors in high-risk post-infarction patients with cardiac autonomic dysfunction and moderately reduced left ventricular ejection fraction A randomized trial View Video | Download Slides

Dr. Stefan Anker and Dr. C. Michael Gibson Discuss: EMPEROR-Preserved: effect of empagliflozin on cardiovascular death and heart failure hospitalizations in patients with heart failure with a preserved ejection fraction, with and without diabetes View Video | Download Slides

EuroPCR 2021

Dr. Arnoud van ’t Hof, Dr. Jur ten Berg and Dr. C. Michael Gibson Discuss: A novel rapid glycoprotein IIb/IIIa inhibitor(RUC-4) for STEMI patients View Video

ACC 2021

Dr. Carolyn Lam reviews the Lancet Commission Report on the Global Cardiovascular Burden in Women and how to improve it View Video

Dr. Roxana Mehran and Dr. C. Michael Gibson Discuss: ACC 2021 Wrap-Up – May 17, 2021 View Video

Dr. John Teerlink and Dr. C. Michael Gibson Discuss: Impact Of Ejection Fraction On The Therapeutic Effect Of Omecamtiv Mecarbil In Patients With Heart Failure And Reduced Ejection Fraction: A Secondary Analysis From GALACTIC-HF View Video | Download Slides

Dr. Cecilia Bahit Presents: ACC 2021 Wrap-up in Spanish View Video

Dr. Paul Ridker and Dr. C. Michael Gibson Discuss: Effects Of Interleukin-6 Inhibition With Ziltivekimab On Biomarkers Of Inflammation Among Patients At High Risk For Atherosclerotic Events View Video | Download Slides

Dr. Kreton Mavromatis and Dr. C. Michael Gibson Discuss: Impact Of Completeness Of Revascularization On Quality-of-life In Patients With Stable Ischemic Heart Disease: Insights From The ISCHEMIA Trial View Video | Download Slides

Dr. Gregg Stone and Dr. C. Michael Gibson Discuss: Impact Of Completeness Of Revascularization On Clinical Outcomes In Patients With Stable Ischemic Heart Disease Treated With An Invasive Vs. Conservative Strategy: The ISCHEMIA Trial View Video | Download Slides

Dr. Gregory Marcus and Dr. C. Michael Gibson Discuss: Acute Alcohol Consumption And Discrete Atrial Fibrillation Events View Video | Download Slides

Dr. Jan Belohlavek and Dr. C. Michael Gibson Discuss: Hyperinvasive Approach In Refractory Out-of-hospital Cardiac Arrest: An Open-label Randomized Controlled Trial. Prague OHCA Study View Video | Download Slides

Dr. Michel Le May and Dr. C. Michael Gibson Discuss: Therapeutic Hypothermia Following Out-Of-Hospital Cardiac Arrest: A Randomized Trial Comparing Mild And Moderate Therapeutic Hypothermia View Video

Dr. Douglas Mann and Dr. C. Michael Gibson Discuss: Sacubitril/Valsartan (LCZ696) In Patients With Advanced Heart Failure And Reduced Ejection Fraction: Results Of The LIFE Trial View Video | Download Slides

Dr. Deepak Bhatt and Dr. C. Michael Gibson Discuss: Benefits Of Sodium Glucose Co-transporter-1/2 Inhibition With Sotagliflozin Across The Full Spectrum Of Ejection Fraction, Including Heart Failure With Preserved Ejection Fraction View Video

Dr. Roxana Mehran and Dr. C. Michael Gibson Discuss: ACC 2021 Wrap-Up May 16, 2021 View Video

Dr. Behnood Bikdeli and Dr. C. Michael Gibson Discuss: Atorvastatin Versus Placebo In Critically-ill Patients With Covid-19: The Inspiration-S Double Blind Randomized Controlled Trial View Video | Download Slides

Dr. Renato Lopes and Dr. C. Michael Gibson Discuss: Randomized Clinical Trial To Evaluate A Routine Full Anticoagulation Strategy In Patients With Coronavirus Infection (SARS-CoV-2) Admitted To Hospital: The Coalition ACTION Trial View Video | Download Slides

Dr. Robert Rosenson and Dr. C. Michael Gibson Discuss: A Phase 2 Trial Of The Efficacy And Safety Of Evinacumab In Patients With Severe Hypertriglyceridemia View Video | Download Slides

Dr. Siri Lagethon Heck and Dr. C. Michael Gibson Discuss: Prevention Of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy (PRADA): Long-term Follow-up Of A 2 X 2 Factorial, Randomized, Placebo-controlled, Double-blind Clinical Trial Of Candesartan And Metoprolol View Video | Download Slides

Dr. Deepak Bhatt and Dr. C. Michael Gibson Discuss: EPA Levels and Outcomes View Video

Dr. Steven Nissen and Dr. C. Michael Gibson Discuss: Relationship Between Omega-3 Fatty Acid Levels And Major Adverse Cardiovascular Outcomes In Patients With High Cardiovascular Risk View Video | Download Slides

Dr. Rupert Bauersachs and Dr. C. Michael Gibson Discuss: Reductions In Total Ischemic Events With Rivaroxaban In Patients With Symptomatic Pad After Revascularization: The VOYAGER PAD Trial View Video | Download Slides

Dr. Mikhail Kosiborod and Dr. C. Michael Gibson Discuss: Effects Of Dapagliflozin On Prevention Of Major Clinical Events And Recovery In Patients With Respiratory Failure Due To COVID-19 Main Results From The DARE-19 Randomized Trial View Video | Download Slides

Dr. Dalane Kitzman and Dr. C. Michael Gibson Discuss: A Novel Physical Rehabilitation Intervention For Older Patients With Acute Decompensated Heart Failure: The REHAB-HF Trial View Video | Download Slides

Dr. Roxana Mehran and Dr. C. Michael Gibson Discuss: ACC 2021 Wrap-Up May 15, 2021 View Video

Dr. Birgit Vogel and Dr. C. Michael Gibson Discuss: Sex-Specific Outcomes In High-Risk Patients Receiving Ticagrelor With Or Without Aspirin After Percutaneous Coronary Intervention: Results From The Twilight Study View Video | Download Slides

Dr. Susheel Kodali and Dr. C. Michael Gibson Discuss: Transfemoral Tricuspid Valve Replacement In Patients With Tricuspid Regurgitation: 30-day Results Of The Triscend Study View Video

Dr. Jean-Philippe Collet, Dr. Gilles Montalescot and Dr. C. Michael Gibson Discuss: Oral Anti-xa Anticoagulation After Trans-aortic Valve Implantation For Aortic Stenosis: The Randomized Atlantis Trial and the 4d Computed Tomography Substudy View Video | Download Slides

Dr. Richard Whitlock and Dr. C. Michael Gibson Discuss: The Left Atrial Appendage Occlusion Study (LAAOS) III View Video | Download Slides

Dr. Schuyler Jones, Mr. Greg Merritt, and Dr. C. Michael Gibson Discuss: Aspirin Dosing: A Patient-centric Trial Assessing Benefits And Long-term Effectiveness Trial View Video | Download Slides

Dr. Eugene Braunwald and Dr. C. Michael Gibson Discuss: Prospective Arni Versus Ace Inhibitor Trial To Determine Superiority In Reducing Heart Failure Events After Myocardial Infarction (paradise-mi) View Video | Download Slides

Coronary Artery Disease

Dr. Dean Kereiakes and Dr. C. Michael Gibson Discuss Shockwave FDA Approval View Video

AHA 2020

Dr. Robert Harrington and Dr. C. Michael Gibson Discuss: The AHA COVID-19 Cardiovascular Disease Registry: Design, Implementation, and Initial Results View Video

Dr. John Teerlink and Dr. C. Michael Gibson Discuss: Omecamtiv Mecarbil in Chronic Heart Failure With Reduced Ejection Fraction: The Global Approach to Lowering Adverse Cardiac Outcomes Through Improving Contractility in Heart Failure (GALACTIC-HF) Trial View Video

Dr. Roxana Mehran and Dr. C. Michael Gibson Discuss: AHA 2020 Daily Wrap-Up November 16, 2020 View Video

Dr. Pierre Amarenco Presents: Ticagrelor Added to Aspirin in Acute Ischemic Stroke or Tia of Atherosclerotic Origin Download Slides

Dr. Deepak Bhatt and Dr. C. Michael Gibson Discuss: Divergent Results in the STRENGTH and REDUCE-IT trials View Video

Dr. Deepak Bhatt and Dr. C. Michael Gibson Discuss: The SOLOIST-WHF and SCORED Trials: Sotagliflozin in Diabetes Patients View Video

Dr. Steven Steinhubl and Dr. C. Michael Gibson Discuss: 3-year Clinical Outcomes In A Nationwide, Randomized, Pragmatic Clinical Trial Of Atrial Fibrillation Screening Mhealth Screening To Prevent Strokes (mstops) View Video

Dr. Alexandra J Lansky Presents: A Prospective Multicenter Randomized Controlled Trial Assessing the Safety and Efficacy of the BuMA Supreme™ Biodegradable Drug Coated Coronary Stent System in Patients With Stable or Non-ST Elevation Acute Coronary Syndromes: Primary Endpoint Results of the PIONEER III Trial Download Slides

Dr. A. Michael Lincoff and Dr. C. Michael Gibson Discuss: STRENGTH Trial: Cardiovascular Outcomes With Omega-3 Carboxylic Acids (Epanova) In Patients With High Vascular Risk And Atherogenic Dyslipidemia View Video

Dr. Otavio Berwanger and Dr. C. Michael Gibson Discuss: Rivaroxaban Versus Warfarin In Patients With Bioprosthetic Mitral Valves And Atrial Fibrillation Or Flutter: Primary Results From The RIVER Randomized Trial View Video | Download Slides

Dr. Renato Lopes and Dr. C. Michael Gibson Discuss: Rivaroxaban Versus Warfarin In Patients With Bioprosthetic Mitral Valves And Atrial Fibrillation Or Flutter: Primary Results From The RIVER Randomized Trial View Video

Dr. Johanne Silvain Presents: Ticagrelor versus Clopidogrel in Elective Percutaneous Coronary Intervention : The Alpheus Trial Download Slides

Dr. Salim Yusuf and Dr. C. Michael Gibson Discuss: Aspirin Alone And In Combination With A Polypill In Cardiovascular Disease Primary Prevention: Results From The International Polycap Study (TIPS)-3 View Video

Dr. Prem Pais and Dr. Serge Korjian Discuss: A Polypill For Primary Prevention Of Cardiovascular Disease In Intermediate Risk People: Results Of The International Polycap Study (TIPS)-3 View Video

TCT 2020

Dr. Catalin Toma and Dr. C. Michael Gibson Discuss: FLASH Registry: Acute Hemodynamic Improvement With Percutaneous Mechanical Thrombectomy in a Real-world Pulmonary Embolism Population View Video | Download Slides

Dr. Ehrin Armstrong and Dr. C. Michael Gibson Discuss: TANGO: A Randomized Dose-Escalation Trial of Temsirolimus Adventitial Delivery to Improve Below the Knee Outcomes View Video | Download Slides

Dr. Andrew Holden and Dr. C. Michel Gibson: ILLUMENATE: Four-Year Results With a Low-Dose Paclitaxel Drug-Coated Balloon in De Novo And Restenotic Femoropopliteal Lesions View Video | Download Slides

Dr. Ajay Kirtane, Dr. Roxana Mehran, Dr. Mamas Mamas and Dr. C. Michael Gibson Discuss: TCT 2020 Daily Wrap-Up October 16, 2020 View Video

Dr. Ajay Kirtane, Dr. Roxana Mehran, Dr. Mamas Mamas and Dr. C. Michael Gibson Discuss: TCT 2020 Daily Wrap-Up October 17, 2020 View Video

Dr. Dean Kereiakes and Dr. C. Michael Gibson Discuss: OPTIMIZE: A Randomized Trial of a Novel, Ultra Low Profile Fixed-Wire DES View Video | Download Slides

Dr. Dean Kereiakes and Dr. C. Michael Gibson Discuss: Disrupt CAD III: Safety and Effectiveness of Intravascular Lithotripsy for Treatment of Severe Coronary Calcification View Video | Download Slides

Dr. Robert Byrne and Dr. C. Michael Gibson Discuss: COBRA-REDUCE: A Randomized Trial of a Thromboresistant Polyzene F-Coated Stent With 14 Days DAPT in High-Bleeding Risk Patients View Video | Download Slides

Dr. Hyo-Soo Kim Presents: Host-Reduce-Polytech-ACS: A Randomized Trial of Durable Polymer vs Bioabsorbable Polymer DES in Patients With Acute Coronary Syndromes Download Slides

Dr. Nils Johnson Presents: The DEFINE-FLOW study combined CFR and FFR assessment Download Slides

Dr. Damien Collison and Dr. C. Michael Gibson Discuss: TARGET FFR: A Randomized Trial of Physiology-Guided PCI Optimization View Video | Download Slides

Dr. Nick Curzen Presents: FORECAST: A Randomized Trial of CTA/FFRCT Decision-making in Patients With Chest Pain Download Slides

Dr. Ajay Kirtane and Dr. C. Michael Gibson Discuss: TCT 2020 Daily Wrap-Up October 15, 2020 View Video

Dr. Junjie Zhang and Dr. C. Michael Gibson Discuss: ULTIMATE: Three-Year Outcomes After IVUS-Guided vs Angiography Guided DES Implantation View Video | Download Slides

Dr. Roxana Mehran and Dr. C. Michael Gibson Discuss: XIENCE 90/28: Assessment of Three-Month and One-Month DAPT After Everolimus-Eluting Stents in High-Bleeding Risk Patients View Video | Download Slides

Dr. Timothy Henry and Dr. C. Michael Gibson Discuss: NACMI: Outcomes From the North American COVID-19 STEMI Registry View Video | Download Slides

Dr. Philipp Lurz and Dr. C. Michael Gibson Discuss: MITHRAS: A Randomized Trial of ASD Closure After TMVr View Video | Download Slides

Dr. Jeffrey Moses and Dr. C. Michael Gibson Discuss: REFLECT II: A Randomized Trial of a Cerebral Embolic Protection Device During TAVR View Video | Download Slides

Dr. Corrado Tamburino and Dr. C. Michael Gibson Discuss: SCOPE II: A Randomized Trial of Two Self-expanding TAVR Bioprostheses View Video | Download Slides

Dr. Georgios Vlachojannis and Dr. C. Michael Gibson Discuss: COMPARE CRUSH: A Randomized Trial of Prehospital Crushed vs Uncrushed Prasugrel in STEMI View Video | Download Slides

Dr. Ajay Kirtane, Dr. Roxana Mehran and Dr. C. Michael Gibson Discuss: TCT 2020 Daily Wrap-Up October 14, 2020 View Video

Dr. Byeong-Keuk Kim and Dr. C. Michael Gibson Discuss: TICO-STEMI: A Randomized Trial of Ticagrelor Monotherapy vs Ticagrelor With Aspirin in STEMIView Video | Download Slides

Dr. Gregg Stone and Dr. C. Michael Gibson Discuss: PROSPECT ABSORB: A Randomized Trial of Interventional Treatment of Vulnerable Plaques View Video | Download Slides

Dr. Gregg Stone and Dr. C. Michael Gibson Discuss: Bivalirudin vs Heparin in Patients With Myocardial Infarction: An Individual Patient Data Pooled Analysis View Video | Download Slides

COVID-19 Videos

Dr. Roxana Mehran and Dr. C. Michael Gibson Discuss: The Second Wave of COVID in New York City View Video

Dr. Victor Tapson, Dr. Gregory Piazza, Dr. Alex Spyropoulos, Dr. Samuel Goldhaber and Dr. C Michael Gibson Discuss: Thrombosis in the Setting of COVID View Video

Dr. Rob Califf and Dr. C. Michael Gibson Discuss: Clinical Trials of the Future View Video

Dr. Robert Harrington and Dr. C. Michael Gibson Discuss: Navigating a Pandemic as a Department of Medicine Chairman View Video

Dr. Renato Lopes and Dr. C. Michael Gibson Discuss: BRACE CORONA Continuing versus Suspending Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers: Impact on Adverse Outcomes in Hospitalized Patients with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) View Video

Dr. Eric Topol and Dr. C. Michael Gibson Discuss: Cytokine Storm and Coronavirus View Video

Dr. Eric Topol and Dr. C. Michael Gibson Discuss: Herd Immunity, Re-infection, Re-activation and Seroprevalence View Video

Dr. Eric Topol and Dr. C. Michael Gibson Discuss: Digital Testing of Heart Rate and Temperature to Identify New Coronavirus Cases View Video

Dr. Eric Topol and Dr. C. Michael Gibson Discuss: Lack of Testing and Protective Gear and Efforts to Organize Young Physicians to Safeguard Their Interests View Video

Dr. Duk-Woo Park and Dr. C. Michael Gibson Discuss: How South Korea was Able to Flatten the Curve in the Coronavirus Epidemic View Video

Dr. Carolyn Lam and Dr. C. Michael Gibson Discuss: Flattening the Coronavirus Curve: Lessons from Singapore View Video

Dr. Dominick Angiolillo and Dr. C. Michael Gibson Discuss: The Impact of Coronavirus on Italian Healthcare View Video

Dr. Ajay Kirtane and Dr. C. Michael Gibson Discuss: Coronavirus Update – March 26, 2020 View Video

Dr. George Dangas and Dr. C. Michael Gibson Discuss: Live Update on the COVID-19 Outbreak from New York View Video

Dr. C. Michael Gibson and Jani Tuomi Discuss: Using Telemedicine to Connect Patients with COVID-19 Testing View Video

ST-Elevation Myocardial Infarction

Dr. Dean Kereiakes and Dr. C. Michael Gibson Discuss: RUC-4, a novel small molecule Platelet GPIIb/IIIa inhibitor designed for subcutaneous point of first contact STEMI treatment View Video

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