Skip to Main ContentIndicationsZOLOFT® (sertraline HCl) is a prescription medication for the treatment, in adults, of Major Depressive Disorder (MDD), Obsessive-Compulsive Disorder (OCD), Panic Disorder, Posttraumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), and Social Anxiety Disorder. It is also approved to treat Obsessive Compulsive Disorder (OCD) in children and adolescents aged 6-17 years.Important Safety InformationPrescribing Info & BOXED WARNINGMedication GuideHealthcare ProfessionalsSign Up SAVINGS Terms and conditions apply. ABOUT TAKING ZOLOFT FAQs RESOURCES
CHOOSE BRAND-NAME ZOLOFT
Clinically proven to treat Major Depressive Disorder (MDD), Panic Disorder and Post-Traumatic Stress Disorder (PTSD), and other conditions*
Prescribed by doctors for over 25 years
Ongoing commitment to product quality and safety monitoring
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*Also indicated for Social Anxiety Disorder, Obsessive-Compulsive Disorder, and Premenstrual Dysphoric Disorder.
IF YOU CHOOSE BRAND-NAME ZOLOFT, MAKE SURE YOU GET THE BRAND NAME
Some pharmacies may fill your brand-name ZOLOFT prescription with a generic version. Follow the steps below to help ensure you receive the brand name your doctor prescribed and, if eligible, save on your prescription.
Ask Your Doctor
Ask your doctor to prescribe brand-name ZOLOFT and to indicate "DAW" (Dispense As Written)—or the language used in your state—on all of your ZOLOFT prescriptions.
Get a Savings Card
Sign up for a Savings Card and, if eligible, pay as little as $4 for brand-name ZOLOFT.*
*Terms and conditions apply.
Check Your Pills
Check your pills to be sure they're brand-name ZOLOFT—not the generic. If you think your brand-name prescription has been filled with a generic, talk to your pharmacist.
Check Your PillsDownload a Tip Sheet SAVINGS Terms and conditions apply.
IMPORTANT SAFETY INFORMATION AND INDICATIONS
WARNING: SUICIDALITY AND ANTIDEPRESSANT DRUGS
ZOLOFT and other antidepressant medicines may increase suicidal thoughts or actions in some people 24 years of age and younger, especially within the first few months of treatment or when the dose is changed. Watch for these changes and call your healthcare provider right away if you notice new or sudden changes in mood, behavior, actions, thoughts, or feelings, especially if severe. Pay particular attention to such changes when ZOLOFT is started or when the dose is changed.
Do not take ZOLOFT if you:
Take a Monoamine Oxidase Inhibitor (MAOI), including linezolid or methylene blue, or if you stopped taking an MAOI in the last 2 weeks. Do not take an MAOI within 2 weeks of stopping ZOLOFT. Ask your doctor or pharmacist if you are not sure if your medicine is an MAOITake Orap® (pimozide) because this can cause serious heart problemsAre allergic to sertraline or any of the inactive ingredients in ZOLOFTTake Antabuse® (disulfiram) (if you are taking the liquid form of ZOLOFT) due to the alcohol content of the liquid form of ZOLOFT
Call a doctor right away if you or a person you know who is taking ZOLOFT has any of the following symptoms, especially if they are new, worse, or worry you:
Attempts to commit suicideActing aggressive or violentNew or worse depressionFeeling agitated, restless, angry, or irritableAn increase in activity or talking more than what is normal for youActing on dangerous impulsesThoughts about suicide or dyingNew or worse anxiety or panic attacksTrouble sleepingOther unusual changes in behavior or mood
Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions. Watch for these changes and call your healthcare provider right away if you notice new or sudden changes in mood, behavior, actions, thoughts, or feelings, especially if severe. Keep all follow-up visits with your healthcare provider and call between visits if you are worried about symptoms.
Before taking ZOLOFT, tell your doctor and pharmacist about all prescription and over-the-counter medications and supplements you take or plan to take, including those to treat migraines, psychiatric disorders (including other antidepressants or amphetamines) to avoid a potentially life-threatening condition called serotonin syndrome, and aspirin and other NSAID pain relievers or other blood thinners because they may increase the risk of bleeding.
Tell your doctor immediately if you
Become severely ill and have some or all of these symptoms: agitation, hallucinations, coma, or other changes in mental status; coordination problems or muscle twitching (overactive reflexes); racing heartbeat, high or low blood pressure; sweating or fever; nausea, vomiting, or diarrhea; muscle tightness, as these may be the symptoms of a life-threatening condition called Serotonin SyndromeHave a rash, hives, swelling, or trouble breathing as these may be the symptoms of an allergic reactionHave seizures or convulsionsHave any increased or unusual bruising or bleeding, especially if you take the blood thinner warfarin (Coumadin®, Jantoven®), a non-steroidal anti-inflammatory drug (NSAID), or aspirinHave a headache; weakness or feeling unsteady; confusion, problems concentrating, thinking, or remembering, as these may be the symptoms of low salt (sodium) levels in the blood (hyponatremia). Elderly people may be at greater risk for thisHave sexual problems (dysfunction). Taking selective serotonin reuptake inhibitors (SSRIs), including ZOLOFT, may cause sexual problems
Do not stop ZOLOFT without first talking to your healthcare provider. Stopping ZOLOFT may cause serious symptoms, including anxiety, irritability, high or low mood, feeling restless or sleepy; headache, sweating, nausea, dizziness; electric shock-like sensations, shaking, and confusion.
Some people are at risk for visual problems such as eye pain, changes in vision, or swelling or redness around the eye. You may want to undergo an eye examination to see if you are at risk and get preventative treatment if you are.
ZOLOFT can cause sleepiness or may affect your ability to make decisions, think clearly, or react quickly. You should not drive, operate heavy machinery, or do other dangerous activities until you know how ZOLOFT affects you.
Drinking alcohol while taking ZOLOFT is not recommended.
Women who are pregnant, plan to become pregnant, or who are breastfeeding should not take ZOLOFT without consulting their physician.
The most common side effects in adults treated with ZOLOFT include:
Nausea, loss of appetite, diarrhea, or indigestionIncreased sweatingTremor or shakingAgitationChange in sleep habits including increased sleepiness or insomniaSexual problems, including decreased libido and ejaculation failureFeeling tired or fatiguedAnxiety
In children and adolescents treated with ZOLOFT, adverse reactions were generally similar to those seen in adults with the following additional side effects: abnormal increase in muscle movement or agitation, nose bleeds, urinary incontinence, aggressive reaction, possible slowed growth rate, and weight change.
INDICATIONS
ZOLOFT is a prescription medication for the treatment, in adults, of Major Depressive Disorder (MDD), Obsessive-Compulsive Disorder (OCD), Panic Disorder, Posttraumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), and Social Anxiety Disorder. It is also approved to treat Obsessive Compulsive Disorder (OCD) in children and adolescents aged 6-17 years.
Product names referenced herein are trademarks of their respective owners.
Please see Full Prescribing Information, including BOXED WARNING and Medication Guide.
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s IMPORTANT SAFETY INFORMATION AND INDICATIONS
WARNING: SUICIDALITY AND ANTIDEPRESSANT DRUGS
ZOLOFT and other antidepressant medicines may increase suicidal thoughts or actions in some people 24 years of age and younger, especially within the first few months of treatment or when the dose is changed. Watch for these changes and call your healthcare provider right away if you notice new or sudden changes in mood, behavior, actions, thoughts, or feelings, especially if severe. Pay particular attention to such changes when ZOLOFT is started or when the dose is changed.
Do not take ZOLOFT if you:
Take a Monoamine Oxidase Inhibitor (MAOI), including linezolid or methylene blue, or if you stopped taking an MAOI in the last 2 weeks. Do not take an MAOI within 2 weeks of stopping ZOLOFT. Ask your doctor or pharmacist if you are not sure if your medicine is an MAOITake Orap® (pimozide) because this can cause serious heart problemsAre allergic to sertraline or any of the inactive ingredients in ZOLOFTTake Antabuse® (disulfiram) (if you are taking the liquid form of ZOLOFT) due to the alcohol content of the liquid form of ZOLOFT
Call a doctor right away if you or a person you know who is taking ZOLOFT has any of the following symptoms, especially if they are new, worse, or worry you:
Attempts to commit suicideActing aggressive or violentNew or worse depressionFeeling agitated, restless, angry, or irritableAn increase in activity or talking more than what is normal for youActing on dangerous impulsesThoughts about suicide or dyingNew or worse anxiety or panic attacksTrouble sleepingOther unusual changes in behavior or mood
Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions. Watch for these changes and call your healthcare provider right away if you notice new or sudden changes in mood, behavior, actions, thoughts, or feelings, especially if severe. Keep all follow-up visits with your healthcare provider and call between visits if you are worried about symptoms.
Before taking ZOLOFT, tell your doctor and pharmacist about all prescription and over-the-counter medications and supplements you take or plan to take, including those to treat migraines, psychiatric disorders (including other antidepressants or amphetamines) to avoid a potentially life-threatening condition called serotonin syndrome, and aspirin and other NSAID pain relievers or other blood thinners because they may increase the risk of bleeding.
Tell your doctor immediately if you
Become severely ill and have some or all of these symptoms: agitation, hallucinations, coma, or other changes in mental status; coordination problems or muscle twitching (overactive reflexes); racing heartbeat, high or low blood pressure; sweating or fever; nausea, vomiting, or diarrhea; muscle tightness, as these may be the symptoms of a life-threatening condition called Serotonin SyndromeHave a rash, hives, swelling, or trouble breathing as these may be the symptoms of an allergic reactionHave seizures or convulsionsHave any increased or unusual bruising or bleeding, especially if you take the blood thinner warfarin (Coumadin®, Jantoven®), a non-steroidal anti-inflammatory drug (NSAID), or aspirinHave a headache; weakness or feeling unsteady; confusion, problems concentrating, thinking, or remembering, as these may be the symptoms of low salt (sodium) levels in the blood (hyponatremia). Elderly people may be at greater risk for thisHave sexual problems (dysfunction). Taking selective serotonin reuptake inhibitors (SSRIs), including ZOLOFT, may cause sexual problems
Do not stop ZOLOFT without first talking to your healthcare provider. Stopping ZOLOFT may cause serious symptoms, including anxiety, irritability, high or low mood, feeling restless or sleepy; headache, sweating, nausea, dizziness; electric shock-like sensations, shaking, and confusion.
Some people are at risk for visual problems such as eye pain, changes in vision, or swelling or redness around the eye. You may want to undergo an eye examination to see if you are at risk and get preventative treatment if you are.
ZOLOFT can cause sleepiness or may affect your ability to make decisions, think clearly, or react quickly. You should not drive, operate heavy machinery, or do other dangerous activities until you know how ZOLOFT affects you.
Drinking alcohol while taking ZOLOFT is not recommended.
Women who are pregnant, plan to become pregnant, or who are breastfeeding should not take ZOLOFT without consulting their physician.
The most common side effects in adults treated with ZOLOFT include:
Nausea, loss of appetite, diarrhea, or indigestionIncreased sweatingTremor or shakingAgitationChange in sleep habits including increased sleepiness or insomniaSexual problems, including decreased libido and ejaculation failureFeeling tired or fatiguedAnxiety
In children and adolescents treated with ZOLOFT, adverse reactions were generally similar to those seen in adults with the following additional side effects: abnormal increase in muscle movement or agitation, nose bleeds, urinary incontinence, aggressive reaction, possible slowed growth rate, and weight change.
INDICATIONS
ZOLOFT is a prescription medication for the treatment, in adults, of Major Depressive Disorder (MDD), Obsessive-Compulsive Disorder (OCD), Panic Disorder, Posttraumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), and Social Anxiety Disorder. It is also approved to treat Obsessive Compulsive Disorder (OCD) in children and adolescents aged 6-17 years.
Product names referenced herein are trademarks of their respective owners.
Please see Full Prescribing Information, including BOXED WARNING and Medication Guide.
